Studies

Orthosilicic Acid Enhances Collagen and Bone Cell Formation
This study demonstrates that orthosilicic acid significantly stimulates collagen type 1 synthesis and promotes osteoblastic differentiation in human bone cells. These effects were especially evident at concentrations of 10–20 μM, suggesting a beneficial role in bone health and regeneration.

Dietary Silicon Intake Improves Bone Density in Men and Premenopausal Women
A population-based study found that higher dietary silicon intake is positively associated with increased bone mineral density, especially in men and premenopausal women. This highlights silicon as a potential key nutrient for maintaining bone health and preventing osteoporosis.

Silicon from Supplements is Better Absorbed than from Food Sources
The comparative study reveals that orthosilicic acid from supplements is more bioavailable than silicon from most food sources, with up to 64% absorption seen in stabilized forms. These findings underscore the importance of supplement formulation in maximizing silicon’s benefits for connective tissue and bone health.